Symplectic integrators are largely employed in MD due to their long-term stability and near conservation of invariants. Their numerical robustness can be rationalized by the existence of a shadow Hamiltonian Hsh, exactly conserved by symplectic …
G-quadruplexes (G4s) are noncanonical nucleic acid structures especially abundant in telomeres, where they can assemble into higher-order multimers. Stabilization of these assemblies is recognized as a promising strategy for suppressing tumor …
Silk fibroin (SF), the primary protein component of Bombyx mori silkworm cocoons, undergoes liquid–liquid phase separation (LLPS), followed by coacervation into fibers, in the silkworm glands. The molecular mechanisms underlying LLPS remain to be …
Attempts to use colloid science concepts to better understand the dynamic properties of concentrated or crowded protein solutions are challenging due to the fact that globular proteins generally have heterogeneous surfaces that result in anisotropic …